Vitamin D supplementation may improve symptoms in Meniere's disease

Bela Büki, Heinz Jünger, Yunxia Wang Lundberg

Research output: Journal article (peer-reviewed)Journal article

Abstract

In the last 4 years the authors observed a trend that correcting vitamin D deficiency in newly diagnosed cases of Meniere's disease decreased the necessity of the ablative therapy with intratympanic gentamicin. According to their hypothesis, vitamin D supplementation may indeed have a beneficial effect in Meniere's disease if the symptoms are caused by a local postviral autoimmune reaction. Vitamin D has a strong immunomodulatory role, one of which is the regulation of the expression of pro-inflammatory mediators. The authors suggest further epidemiological studies to decide if there is a connection between vitamin D deficiency and Meniere's disease.

Original languageEnglish
Pages (from-to)44-46
Number of pages3
JournalMedical Hypotheses
Volume116
DOIs
Publication statusPublished - Jul 2018

Keywords

  • Anti-Bacterial Agents/therapeutic use
  • Autoimmunity
  • Cytokines/metabolism
  • Dietary Supplements
  • Gentamicins/therapeutic use
  • Humans
  • Inflammation
  • Meniere Disease/complications
  • Models, Theoretical
  • Vertigo
  • Vitamin D/analogs & derivatives
  • Vitamin D Deficiency/complications

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