Retraction: Mechanisms by which SGN-40, a Humanized Anti-CD40 Antibody, Induces Cytotoxicity in Human Multiple Myeloma Cells: Clinical Implications

Yu-Tzu Tai, Laurence P Catley, Constantine S Mitsiades, Renate Burger, Klaus Podar, Reshma Shringpaure, Teru Hideshima, Dharminder Chauhan, Makoto Hamasaki, Kenji Ishitsuka, Paul Richardson, Steven P Treon, Nikhil C Munshi, Kenneth C Anderson

Research output: Journal article (peer-reviewed)Journal article

Abstract

This article (1) has been retracted at the request of the authors. There are concerns about the reliability of certain data arising from errors in the assembly of Fig. 2. In Fig. 2A, the same image was used in lanes 2-5 to represent lkBa in cells treated with SGN-40 and in lanes 1-4 to represent lkBa in cells treated with sCD40L. In Fig. 2B, the same image was used in lanes 2 and 5 to represent pAKT in distinct samples and treatment conditions. The authors apologize to the scientific community, deeply regret any inconveniences or challenges resulting from the publication and subsequent retraction of this article, and have implemented various quality checks to avoid a future recurrence. A copy of this Retraction Notice was sent to the last known email addresses for 13 of the 14 authors. Seven authors (Yu-Tzu Tai, Constantine S. Mitsiades, Klaus Podar, Dharminder Chauhan, Kenji Ishitsuka, Steven P. Treon, Kenneth C. Anderson) agreed to the retraction; 6 authors (Renate Burger, Reshma Shringpaure, Teru Hideshima, Makoto Hamasaki, Paul Richardson, Nikhil C. Munshi) did not respond; the one remaining author (Laurence P. Catley) is deceased.

Original languageEnglish
Pages (from-to)936
Number of pages1
JournalCancer Research
Volume84
Issue number6
DOIs
Publication statusPublished - 15 Mar 2024
Externally publishedYes

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