Recent developments and highlights in mechanisms of allergic diseases: Microbiome

Nonhlanhla Lunjani; Pattraporn Satitsuksanoa; Zuzanna Lukasik; Milena Sokolowska; Thomas Eiwegger; Liam O'Mahony

doi:10.1111/all.13634

Recent developments and highlights in mechanisms of allergic diseases: Microbiome

Nonhlanhla Lunjani, Pattraporn Satitsuksanoa, Zuzanna Lukasik, Milena Sokolowska, Thomas Eiwegger, Liam O'Mahony

Research output: Journal article (peer-reviewed) › Review article

90 Citations (Scopus)

Abstract

All body surfaces are exposed to a wide variety of microbes, which significantly influence immune reactivity within the host. This review provides an update on some of the critical novel findings that have been published on the influence of the microbiome on atopic dermatitis, food allergy and asthma. Microbial dysbiosis has consistently been observed in the skin, gut and lungs of patients with atopic dermatitis, food allergy and asthma, respectively, and the role of specific microbes in allergic disorders is being intensively investigated. However, many of these discoveries have yet to be translated into routine clinical practice.

Original language	English
Pages (from-to)	2314-2327
Number of pages	14
Journal	Allergy: European Journal of Allergy and Clinical Immunology
Volume	73
Issue number	12
DOIs	https://doi.org/10.1111/all.13634
Publication status	Published - Dec 2018
Externally published	Yes

Keywords

Asthma/microbiology
Dermatitis, Atopic/microbiology
Dysbiosis
Food Hypersensitivity/microbiology
Humans
Hypersensitivity/microbiology
Microbiota/immunology

Access to Document

10.1111/all.13634

Cite this

@article{3e05f768a58a4233bd6fd9ec3a90a545,

title = "Recent developments and highlights in mechanisms of allergic diseases: Microbiome",

abstract = "All body surfaces are exposed to a wide variety of microbes, which significantly influence immune reactivity within the host. This review provides an update on some of the critical novel findings that have been published on the influence of the microbiome on atopic dermatitis, food allergy and asthma. Microbial dysbiosis has consistently been observed in the skin, gut and lungs of patients with atopic dermatitis, food allergy and asthma, respectively, and the role of specific microbes in allergic disorders is being intensively investigated. However, many of these discoveries have yet to be translated into routine clinical practice.",

keywords = "Asthma/microbiology, Dermatitis, Atopic/microbiology, Dysbiosis, Food Hypersensitivity/microbiology, Humans, Hypersensitivity/microbiology, Microbiota/immunology",

author = "Nonhlanhla Lunjani and Pattraporn Satitsuksanoa and Zuzanna Lukasik and Milena Sokolowska and Thomas Eiwegger and Liam O'Mahony",

note = "Publisher Copyright: {\textcopyright} 2018 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.",

year = "2018",

month = dec,

doi = "10.1111/all.13634",

language = "English",

volume = "73",

pages = "2314--2327",

journal = "Allergy: European Journal of Allergy and Clinical Immunology",

issn = "0105-4538",

publisher = "Wiley-Blackwell Publishing Ltd",

number = "12",

}

TY - JOUR

T1 - Recent developments and highlights in mechanisms of allergic diseases

T2 - Microbiome

AU - Lunjani, Nonhlanhla

AU - Satitsuksanoa, Pattraporn

AU - Lukasik, Zuzanna

AU - Sokolowska, Milena

AU - Eiwegger, Thomas

AU - O'Mahony, Liam

PY - 2018/12

Y1 - 2018/12

N2 - All body surfaces are exposed to a wide variety of microbes, which significantly influence immune reactivity within the host. This review provides an update on some of the critical novel findings that have been published on the influence of the microbiome on atopic dermatitis, food allergy and asthma. Microbial dysbiosis has consistently been observed in the skin, gut and lungs of patients with atopic dermatitis, food allergy and asthma, respectively, and the role of specific microbes in allergic disorders is being intensively investigated. However, many of these discoveries have yet to be translated into routine clinical practice.

AB - All body surfaces are exposed to a wide variety of microbes, which significantly influence immune reactivity within the host. This review provides an update on some of the critical novel findings that have been published on the influence of the microbiome on atopic dermatitis, food allergy and asthma. Microbial dysbiosis has consistently been observed in the skin, gut and lungs of patients with atopic dermatitis, food allergy and asthma, respectively, and the role of specific microbes in allergic disorders is being intensively investigated. However, many of these discoveries have yet to be translated into routine clinical practice.

KW - Asthma/microbiology

KW - Dermatitis, Atopic/microbiology

KW - Dysbiosis

KW - Food Hypersensitivity/microbiology

KW - Humans

KW - Hypersensitivity/microbiology

KW - Microbiota/immunology

UR - http://www.scopus.com/inward/record.url?scp=85056462716&partnerID=8YFLogxK

U2 - 10.1111/all.13634

DO - 10.1111/all.13634

M3 - Review article

C2 - 30325537

SN - 0105-4538

VL - 73

SP - 2314

EP - 2327

JO - Allergy: European Journal of Allergy and Clinical Immunology

JF - Allergy: European Journal of Allergy and Clinical Immunology

IS - 12

ER -

Recent developments and highlights in mechanisms of allergic diseases: Microbiome

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this