Randomized comparison between KTd and KRd induction therapy followed by maintenance therapy with K or observation in transplant-ineligible patients with newly diagnosed multiple myeloma

Heinz Ludwig; Thomas Melchardt; Siegfried Sormann; Martin Schreder; Johannes Andel; Bernd Hartmann; Christoph Tinchon; Niklas Zojer; Eberhard Gunsilius; Klaus Podar; Alexander Egle; Wolfgang Willenbacher; Ewald Wöll; Reinhard Ruckser; Boris Bozic; Maria-Theresa Krauth; Andreas Petzer; Clemens Schmitt; Sigrid Machherndl-Spandl; Hermine Agis; Michael Fillitz; Song-Yau Wang; August Zabernigg; Stefan Knop; Bruno Paiva; Richard Greil

doi:10.1002/ajh.27280

Randomized comparison between KTd and KRd induction therapy followed by maintenance therapy with K or observation in transplant-ineligible patients with newly diagnosed multiple myeloma

Heinz Ludwig^*
, Thomas Melchardt
, Siegfried Sormann
, Martin Schreder
, Johannes Andel
, Bernd Hartmann
, Christoph Tinchon
, Niklas Zojer
, Eberhard Gunsilius
, Klaus Podar
, Alexander Egle
, Wolfgang Willenbacher
, Ewald Wöll
, Reinhard Ruckser
, Boris Bozic
, Maria-Theresa Krauth
, Andreas Petzer
, Clemens Schmitt
, Sigrid Machherndl-Spandl
, Hermine Agis

Michael Fillitz, Song-Yau Wang, August Zabernigg, Stefan Knop, Bruno Paiva, Richard Greil

^*Corresponding author for this work

Research output: Journal article (peer-reviewed) › Letter/short communication

3 Citations (Scopus)

Abstract

Randomized comparison between KTd and KRd induction followed by second randomization to carfilzomib in transplant-ineligable patients with newly diagnosed multiple myeloma.

Original language	English
Pages (from-to)	1008-1011
Number of pages	4
Journal	American Journal of Hematology
Volume	99
Issue number	5
Early online date	29 Feb 2024
DOIs	https://doi.org/10.1002/ajh.27280
Publication status	Published - May 2024

Keywords

Lenalidomide/therapeutic use
Dexamethasone/therapeutic use
Humans
Induction Chemotherapy
Antineoplastic Combined Chemotherapy Protocols/adverse effects
Multiple Myeloma/diagnosis

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10.1002/ajh.27280

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Ludwig, H., Melchardt, T., Sormann, S., Schreder, M., Andel, J., Hartmann, B., Tinchon, C., Zojer, N., Gunsilius, E., Podar, K., Egle, A., Willenbacher, W., Wöll, E., Ruckser, R., Bozic, B., Krauth, M.-T., Petzer, A., Schmitt, C., Machherndl-Spandl, S., ... Greil, R. (2024). Randomized comparison between KTd and KRd induction therapy followed by maintenance therapy with K or observation in transplant-ineligible patients with newly diagnosed multiple myeloma. American Journal of Hematology, 99(5), 1008-1011. https://doi.org/10.1002/ajh.27280

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title = "Randomized comparison between KTd and KRd induction therapy followed by maintenance therapy with K or observation in transplant-ineligible patients with newly diagnosed multiple myeloma",

abstract = "Randomized comparison between KTd and KRd induction followed by second randomization to carfilzomib in transplant-ineligable patients with newly diagnosed multiple myeloma.",

keywords = "Lenalidomide/therapeutic use, Dexamethasone/therapeutic use, Humans, Induction Chemotherapy, Antineoplastic Combined Chemotherapy Protocols/adverse effects, Multiple Myeloma/diagnosis",

author = "Heinz Ludwig and Thomas Melchardt and Siegfried Sormann and Martin Schreder and Johannes Andel and Bernd Hartmann and Christoph Tinchon and Niklas Zojer and Eberhard Gunsilius and Klaus Podar and Alexander Egle and Wolfgang Willenbacher and Ewald W{\"o}ll and Reinhard Ruckser and Boris Bozic and Maria-Theresa Krauth and Andreas Petzer and Clemens Schmitt and Sigrid Machherndl-Spandl and Hermine Agis and Michael Fillitz and Song-Yau Wang and August Zabernigg and Stefan Knop and Bruno Paiva and Richard Greil",

note = "{\textcopyright} 2024 Wiley Periodicals LLC.",

year = "2024",

month = may,

doi = "10.1002/ajh.27280",

language = "English",

volume = "99",

pages = "1008--1011",

journal = "American Journal of Hematology",

issn = "0361-8609",

publisher = "John Wiley and Sons Inc.",

number = "5",

}

Ludwig, H, Melchardt, T, Sormann, S, Schreder, M, Andel, J, Hartmann, B, Tinchon, C, Zojer, N, Gunsilius, E, Podar, K, Egle, A, Willenbacher, W, Wöll, E, Ruckser, R, Bozic, B, Krauth, M-T, Petzer, A, Schmitt, C, Machherndl-Spandl, S, Agis, H, Fillitz, M, Wang, S-Y, Zabernigg, A, Knop, S, Paiva, B & Greil, R 2024, 'Randomized comparison between KTd and KRd induction therapy followed by maintenance therapy with K or observation in transplant-ineligible patients with newly diagnosed multiple myeloma', American Journal of Hematology, vol. 99, no. 5, pp. 1008-1011. https://doi.org/10.1002/ajh.27280

Randomized comparison between KTd and KRd induction therapy followed by maintenance therapy with K or observation in transplant-ineligible patients with newly diagnosed multiple myeloma. / Ludwig, Heinz; Melchardt, Thomas; Sormann, Siegfried et al.
In: American Journal of Hematology, Vol. 99, No. 5, 05.2024, p. 1008-1011.

Research output: Journal article (peer-reviewed) › Letter/short communication

TY - JOUR

T1 - Randomized comparison between KTd and KRd induction therapy followed by maintenance therapy with K or observation in transplant-ineligible patients with newly diagnosed multiple myeloma

AU - Ludwig, Heinz

AU - Melchardt, Thomas

AU - Sormann, Siegfried

AU - Schreder, Martin

AU - Andel, Johannes

AU - Hartmann, Bernd

AU - Tinchon, Christoph

AU - Zojer, Niklas

AU - Gunsilius, Eberhard

AU - Podar, Klaus

AU - Egle, Alexander

AU - Willenbacher, Wolfgang

AU - Wöll, Ewald

AU - Ruckser, Reinhard

AU - Bozic, Boris

AU - Krauth, Maria-Theresa

AU - Petzer, Andreas

AU - Schmitt, Clemens

AU - Machherndl-Spandl, Sigrid

AU - Agis, Hermine

AU - Fillitz, Michael

AU - Wang, Song-Yau

AU - Zabernigg, August

AU - Knop, Stefan

AU - Paiva, Bruno

AU - Greil, Richard

PY - 2024/5

Y1 - 2024/5

N2 - Randomized comparison between KTd and KRd induction followed by second randomization to carfilzomib in transplant-ineligable patients with newly diagnosed multiple myeloma.

AB - Randomized comparison between KTd and KRd induction followed by second randomization to carfilzomib in transplant-ineligable patients with newly diagnosed multiple myeloma.

KW - Lenalidomide/therapeutic use

KW - Dexamethasone/therapeutic use

KW - Humans

KW - Induction Chemotherapy

KW - Antineoplastic Combined Chemotherapy Protocols/adverse effects

KW - Multiple Myeloma/diagnosis

UR - https://www.scopus.com/pages/publications/85186872616

U2 - 10.1002/ajh.27280

DO - 10.1002/ajh.27280

M3 - Letter/short communication

C2 - 38425185

SN - 0361-8609

VL - 99

SP - 1008

EP - 1011

JO - American Journal of Hematology

JF - American Journal of Hematology

IS - 5

ER -

Randomized comparison between KTd and KRd induction therapy followed by maintenance therapy with K or observation in transplant-ineligible patients with newly diagnosed multiple myeloma

Abstract

Keywords

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