Pathobiologie und Genetik

Christina A. Eichstaedt; Andrea Olschewski; Lars Harbaum; Sebastian Cordes; Peter Dorfmüller; Vasile Foris; Wolfgang M. Kuebler; Grazyna Kwapiszewska; Soni Pullamsetti; Natascha Sommer; Christoph Tabeling; Norbert Weissmann; Anja Zoll; Katrin Hinderhofer; Ralph T. Schermuly

doi:10.1055/a-2625-4648

Pathobiologie und Genetik

Translated title of the contribution: Pathobiology and Genetics

Christina A. Eichstaedt
, Andrea Olschewski
, Lars Harbaum
, Sebastian Cordes
, Peter Dorfmüller
, Vasile Foris
, Wolfgang M. Kuebler
, Grazyna Kwapiszewska
, Soni Pullamsetti
, Natascha Sommer
, Christoph Tabeling
, Norbert Weissmann
, Anja Zoll
, Katrin Hinderhofer
, Ralph T. Schermuly^*

^*Corresponding author for this work

Research output: Journal article (peer-reviewed) › Journal article

Abstract

Genetics and pathobiology were addressed at the 7 ^thWorld Symposium on Pulmonary Hypertension in Task Forces 2 and 3. The Genetics Task Force also focused on precision medicine approaches, and the Pathobiology working group concentrated heavily on new omics technologies. Therefore, the following not only summarises the current state of knowledge on genetics, genetic testing methods, and molecular pathophysiological changes, but also places it in context and critically discusses it. In addition, the importance of national and international biobanks and cohorts, as well as the active involvement of patients and families, is emphasized.

Translated title of the contribution	Pathobiology and Genetics
Original language	German
Pages (from-to)	701-711
Number of pages	11
Journal	Pneumologie
Volume	79
Issue number	10
DOIs	https://doi.org/10.1055/a-2625-4648
Publication status	Published - 01 Oct 2025
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

Access to Document

10.1055/a-2625-4648

Cite this

@article{716b590523714ade89df247cafe723df,

title = "Pathobiologie und Genetik",

abstract = "Genetics and pathobiology were addressed at the 7 thWorld Symposium on Pulmonary Hypertension in Task Forces 2 and 3. The Genetics Task Force also focused on precision medicine approaches, and the Pathobiology working group concentrated heavily on new omics technologies. Therefore, the following not only summarises the current state of knowledge on genetics, genetic testing methods, and molecular pathophysiological changes, but also places it in context and critically discusses it. In addition, the importance of national and international biobanks and cohorts, as well as the active involvement of patients and families, is emphasized.",

keywords = "biobanks, BMPR2, genetic diagnostics, multi-omics, Hypertension, Pulmonary/genetics, Genetic Testing/methods, Humans, Genetic Predisposition to Disease/genetics, Precision Medicine/trends",

author = "Eichstaedt, \{Christina A.\} and Andrea Olschewski and Lars Harbaum and Sebastian Cordes and Peter Dorfm{\"u}ller and Vasile Foris and Kuebler, \{Wolfgang M.\} and Grazyna Kwapiszewska and Soni Pullamsetti and Natascha Sommer and Christoph Tabeling and Norbert Weissmann and Anja Zoll and Katrin Hinderhofer and Schermuly, \{Ralph T.\}",

year = "2025",

month = oct,

day = "1",

doi = "10.1055/a-2625-4648",

language = "Deutsch",

volume = "79",

pages = "701--711",

journal = "Pneumologie",

issn = "0934-8387",

publisher = "Georg Thieme Verlag",

number = "10",

}

TY - JOUR

T1 - Pathobiologie und Genetik

AU - Eichstaedt, Christina A.

AU - Olschewski, Andrea

AU - Harbaum, Lars

AU - Cordes, Sebastian

AU - Dorfmüller, Peter

AU - Foris, Vasile

AU - Kuebler, Wolfgang M.

AU - Kwapiszewska, Grazyna

AU - Pullamsetti, Soni

AU - Sommer, Natascha

AU - Tabeling, Christoph

AU - Weissmann, Norbert

AU - Zoll, Anja

AU - Hinderhofer, Katrin

AU - Schermuly, Ralph T.

PY - 2025/10/1

Y1 - 2025/10/1

N2 - Genetics and pathobiology were addressed at the 7 thWorld Symposium on Pulmonary Hypertension in Task Forces 2 and 3. The Genetics Task Force also focused on precision medicine approaches, and the Pathobiology working group concentrated heavily on new omics technologies. Therefore, the following not only summarises the current state of knowledge on genetics, genetic testing methods, and molecular pathophysiological changes, but also places it in context and critically discusses it. In addition, the importance of national and international biobanks and cohorts, as well as the active involvement of patients and families, is emphasized.

AB - Genetics and pathobiology were addressed at the 7 thWorld Symposium on Pulmonary Hypertension in Task Forces 2 and 3. The Genetics Task Force also focused on precision medicine approaches, and the Pathobiology working group concentrated heavily on new omics technologies. Therefore, the following not only summarises the current state of knowledge on genetics, genetic testing methods, and molecular pathophysiological changes, but also places it in context and critically discusses it. In addition, the importance of national and international biobanks and cohorts, as well as the active involvement of patients and families, is emphasized.

KW - biobanks

KW - BMPR2

KW - genetic diagnostics

KW - multi-omics

KW - Hypertension, Pulmonary/genetics

KW - Genetic Testing/methods

KW - Humans

KW - Genetic Predisposition to Disease/genetics

KW - Precision Medicine/trends

UR - https://www.scopus.com/pages/publications/105017936235

U2 - 10.1055/a-2625-4648

DO - 10.1055/a-2625-4648

M3 - Artikel in Fachzeitschrift

C2 - 41052524

AN - SCOPUS:105017936235

SN - 0934-8387

VL - 79

SP - 701

EP - 711

JO - Pneumologie

JF - Pneumologie

IS - 10

ER -

Pathobiologie und Genetik

Abstract

UN SDGs

ASJC Scopus subject areas

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