Myalgische Enzephalomyelitis/chronisches Fatigue-Syndrom: eine Übersicht zur aktuellen Evidenz

Translated title of the contribution: Myalgic encephalomyelitis/chronic fatigue syndrome: an overview of current evidence

Birgit Ludwig, Elisabeth Olbert, Karin Trimmel, Stefan Seidel, Paulus S Rommer, Christian Müller, Walter Struhal, Thomas Berger

Research output: Journal article (peer-reviewed)Review article

6 Citations (Scopus)


Over the past 5 years both media and scientific interest has surged regarding the disorder myalgic encephalomyelitis and chronic fatigue syndrome (ME/CFS), not least because of the clinically similar manifestation in long COVID or post-COVID. In this review we discuss the process of clinical diagnosis and randomized controlled therapeutic studies on ME/CFS, and the similarities or differences to long COVID and post-COVID. So far, neither clear pathophysiologically causal nor therapeutic evidence-based results on ME/CFS have been identified in the many years of scientific research. Given the evident psychiatric comorbidity rates in patients with a diagnosis of ME/CFS, a psychosomatic etiology of this syndrome should be considered. Furthermore, a precise and reliable diagnostic classification based on stricter criteria would benefit both pathophysiological and therapeutic research.

Translated title of the contributionMyalgic encephalomyelitis/chronic fatigue syndrome: an overview of current evidence
Original languageGerman
Pages (from-to)725-733
Number of pages9
JournalDer Nervenarzt
Issue number8
Early online date25 Jan 2023
Publication statusPublished - Aug 2023


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