Myalgische Enzephalomyelitis/chronisches Fatigue-Syndrom: eine Übersicht zur aktuellen Evidenz

Birgit Ludwig; Elisabeth Olbert; Karin Trimmel; Stefan Seidel; Paulus S Rommer; Christian Müller; Walter Struhal; Thomas Berger

doi:10.1007/s00115-022-01431-x

Myalgische Enzephalomyelitis/chronisches Fatigue-Syndrom: eine Übersicht zur aktuellen Evidenz

Translated title of the contribution: Myalgic encephalomyelitis/chronic fatigue syndrome: an overview of current evidence

Birgit Ludwig, Elisabeth Olbert, Karin Trimmel, Stefan Seidel, Paulus S Rommer, Christian Müller, Walter Struhal, Thomas Berger

Division of Neurology (University Hospital Tulln)

Research output: Journal article (peer-reviewed) › Review article

Abstract

Over the past 5 years both media and scientific interest has surged regarding the disorder myalgic encephalomyelitis and chronic fatigue syndrome (ME/CFS), not least because of the clinically similar manifestation in long COVID or post-COVID. In this review we discuss the process of clinical diagnosis and randomized controlled therapeutic studies on ME/CFS, and the similarities or differences to long COVID and post-COVID. So far, neither clear pathophysiologically causal nor therapeutic evidence-based results on ME/CFS have been identified in the many years of scientific research. Given the evident psychiatric comorbidity rates in patients with a diagnosis of ME/CFS, a psychosomatic etiology of this syndrome should be considered. Furthermore, a precise and reliable diagnostic classification based on stricter criteria would benefit both pathophysiological and therapeutic research.

Translated title of the contribution	Myalgic encephalomyelitis/chronic fatigue syndrome: an overview of current evidence
Original language	German
Pages (from-to)	1-9
Number of pages	9
Journal	Der Nervenarzt
Early online date	25 Jan 2023
DOIs	https://doi.org/10.1007/s00115-022-01431-x
Publication status	E-pub ahead of print - 25 Jan 2023

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title = "Myalgische Enzephalomyelitis/chronisches Fatigue-Syndrom: eine {\"U}bersicht zur aktuellen Evidenz",

abstract = "Over the past 5 years both media and scientific interest has surged regarding the disorder myalgic encephalomyelitis and chronic fatigue syndrome (ME/CFS), not least because of the clinically similar manifestation in long COVID or post-COVID. In this review we discuss the process of clinical diagnosis and randomized controlled therapeutic studies on ME/CFS, and the similarities or differences to long COVID and post-COVID. So far, neither clear pathophysiologically causal nor therapeutic evidence-based results on ME/CFS have been identified in the many years of scientific research. Given the evident psychiatric comorbidity rates in patients with a diagnosis of ME/CFS, a psychosomatic etiology of this syndrome should be considered. Furthermore, a precise and reliable diagnostic classification based on stricter criteria would benefit both pathophysiological and therapeutic research.",

author = "Birgit Ludwig and Elisabeth Olbert and Karin Trimmel and Stefan Seidel and Rommer, {Paulus S} and Christian M{\"u}ller and Walter Struhal and Thomas Berger",

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AU - Ludwig, Birgit

AU - Olbert, Elisabeth

AU - Trimmel, Karin

AU - Seidel, Stefan

AU - Rommer, Paulus S

AU - Müller, Christian

AU - Struhal, Walter

AU - Berger, Thomas

PY - 2023/1/25

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N2 - Over the past 5 years both media and scientific interest has surged regarding the disorder myalgic encephalomyelitis and chronic fatigue syndrome (ME/CFS), not least because of the clinically similar manifestation in long COVID or post-COVID. In this review we discuss the process of clinical diagnosis and randomized controlled therapeutic studies on ME/CFS, and the similarities or differences to long COVID and post-COVID. So far, neither clear pathophysiologically causal nor therapeutic evidence-based results on ME/CFS have been identified in the many years of scientific research. Given the evident psychiatric comorbidity rates in patients with a diagnosis of ME/CFS, a psychosomatic etiology of this syndrome should be considered. Furthermore, a precise and reliable diagnostic classification based on stricter criteria would benefit both pathophysiological and therapeutic research.

AB - Over the past 5 years both media and scientific interest has surged regarding the disorder myalgic encephalomyelitis and chronic fatigue syndrome (ME/CFS), not least because of the clinically similar manifestation in long COVID or post-COVID. In this review we discuss the process of clinical diagnosis and randomized controlled therapeutic studies on ME/CFS, and the similarities or differences to long COVID and post-COVID. So far, neither clear pathophysiologically causal nor therapeutic evidence-based results on ME/CFS have been identified in the many years of scientific research. Given the evident psychiatric comorbidity rates in patients with a diagnosis of ME/CFS, a psychosomatic etiology of this syndrome should be considered. Furthermore, a precise and reliable diagnostic classification based on stricter criteria would benefit both pathophysiological and therapeutic research.

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Myalgische Enzephalomyelitis/chronisches Fatigue-Syndrom: eine Übersicht zur aktuellen Evidenz

Abstract

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