Mechanical properties of the everolimus-eluting bioresorbable vascular scaffold compared to the metallic everolimus-eluting stent

Daniel Dalos, Clemens Gangl, Christian Roth, Lisa Krenn, Sabine Scherzer, Markus Vertesich, Irene Lang, Gerald Maurer, Thomas Neunteufl, Rudolf Berger, Georg Delle-Karth

Research output: Journal article (peer-reviewed)Journal article

12 Citations (Scopus)


BACKGROUND: Everolimus-eluting bioresorbable vascular scaffolds (BVS) represent an innovative treatment option for coronary artery disease. Clinical and angiographic results seem promising, however, data on its immediate procedural performance are still scarce. The aim of our study was to assess the mechanical properties of BVS by Optical Coherence Tomography (OCT) in clinical routine.

METHODS: Post-implantation OCT images of 40 BVS were retrospectively compared to those of 40 metallic everolimus-eluting stents (EES). Post-procedural device related morphological features were assessed. This included incidences of gross underexpansion and the stent eccentricity index (SEI, minimum/maximum diameter) as a measure for focal radial strength.

RESULTS: Patients receiving BVS were younger than those with EES (54.0 ± 11.2 years versus 61.7 ± 11.4 years, p = 0.012), the remaining baseline, vessel and lesion characteristics were comparable between groups. Lesion pre-dilatation was more frequently performed and inflation time was longer in the BVS than in the EES group (n = 34 versus n = 23, p = 0.006 and 44.2 ± 12.8 versus 25.6 ± 8.4 seconds, p < 0.001, respectively). There were no significant differences in maximal inflation pressures and post-dilatation frequencies with non-compliant balloons between groups. Whereas gross device underexpansion was not significantly different, SEI was significantly lower in the BVS group (n = 12 (30 %) versus n = 14 (35 %), p = 0.812 and 0.69 ± 0.08 versus 0.76 ± 0.09, p < 0.001, respectively). There was no difference in major adverse cardiac event-rate at six months.

CONCLUSION: Our data show that focal radial expansion was significantly reduced in BVS compared to EES in a clinical routine setting using no routine post-dilatation protocol. Whether these findings have impact on scaffold mid-term results as well as on clinical outcome has to be investigated in larger, randomized trials.

Original languageEnglish
Article number104
Pages (from-to)104
JournalBMC Cardiovascular Disorders
Issue number1
Publication statusPublished - 25 May 2016


  • Absorbable Implants
  • Adult
  • Aged
  • Angioplasty, Balloon, Coronary/adverse effects
  • Cardiovascular Agents/administration & dosage
  • Coronary Artery Disease/diagnostic imaging
  • Coronary Vessels/diagnostic imaging
  • Drug-Eluting Stents
  • Everolimus/administration & dosage
  • Female
  • Humans
  • Male
  • Metals
  • Middle Aged
  • Predictive Value of Tests
  • Prosthesis Design
  • Retrospective Studies
  • Time Factors
  • Tomography, Optical Coherence
  • Treatment Outcome
  • Drug-Eluting Stent
  • Optical Coherence Tomography
  • Bioresorbable Scaffold

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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