TY - JOUR
T1 - Long-term performance of an atrial lead capable of accelerometer based detection of cardiac contractility in patients receiving cardiac resynchronisation therapy
AU - Senoner, Thomas
AU - Barbieri, Fabian
AU - Semmler, Georg
AU - Adukauskaite, Agne
AU - Rubatscher, Andrea
AU - Schgör, Wilfried
AU - Stühlinger, Markus
AU - Bauer, Axel
AU - Pfeifer, Bernhard Erich
AU - Fiedler, Lukas
AU - Roithinger, Franz Xaver
AU - Hintringer, Florian
AU - Suessenbacher, Alois
AU - Wollmann, Christian Georg
AU - Dichtl, Wolfgang
N1 - Publisher Copyright:
© 2019 Senoner et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2019/9/1
Y1 - 2019/9/1
N2 - OBJECTIVES: To evaluate the long-term performance of the SonRtip atrial lead.BACKGROUND: To optimize atrioventricular and interventricular timing and thereby potentially improving cardiac resynchronization therapy (CRT) responder rates, a lead integrated technology and a cardioverter/defibrillator-based algorithm measuring peak endocardial acceleration have been introduced. Long-term performance of the atrial lead (SonRtip PS55D, Sorin/MicroPort CRM, Italy) embedded with such a sensor has not been reported so far.METHODS: Between 2012 and 2018, 143 patients underwent implantation of the SonRtip atrial lead in four Austrian medical centers. Conventional bipolar atrial leads implanted during the same period in 526 patients receiving CRT were used as control cohort.RESULTS: Among 669 patients included in the study, 10 (1.5%) showed increased atrial pacing thresholds and/or decreased atrial sensing amplitudes and/or sudden increase in atrial lead impedance (above 3000 Ω) after an uneventful early postoperative period. Seven (70%) of the malfunctioning leads were SonRtip leads (p <0.001). Lead replacement was needed in 4.2% of SonRtip leads (six out of 143) and in 0.38% of all other conventional atrial leads (two out of 526) (p <0.001). Because of unaltered atrial sensing properties, a wait and see strategy was chosen in two patients-one of them with a SonRtip lead. The implanted atrial lead in the latter person experienced a sudden increase in pacing threshold (4V/0.35ms).CONCLUSIONS: While short-term safety and stable technical performance of the SonRtip atrial lead could be confirmed, our study found an unexpectedly high malfunction rate over a longer follow-up period.
AB - OBJECTIVES: To evaluate the long-term performance of the SonRtip atrial lead.BACKGROUND: To optimize atrioventricular and interventricular timing and thereby potentially improving cardiac resynchronization therapy (CRT) responder rates, a lead integrated technology and a cardioverter/defibrillator-based algorithm measuring peak endocardial acceleration have been introduced. Long-term performance of the atrial lead (SonRtip PS55D, Sorin/MicroPort CRM, Italy) embedded with such a sensor has not been reported so far.METHODS: Between 2012 and 2018, 143 patients underwent implantation of the SonRtip atrial lead in four Austrian medical centers. Conventional bipolar atrial leads implanted during the same period in 526 patients receiving CRT were used as control cohort.RESULTS: Among 669 patients included in the study, 10 (1.5%) showed increased atrial pacing thresholds and/or decreased atrial sensing amplitudes and/or sudden increase in atrial lead impedance (above 3000 Ω) after an uneventful early postoperative period. Seven (70%) of the malfunctioning leads were SonRtip leads (p <0.001). Lead replacement was needed in 4.2% of SonRtip leads (six out of 143) and in 0.38% of all other conventional atrial leads (two out of 526) (p <0.001). Because of unaltered atrial sensing properties, a wait and see strategy was chosen in two patients-one of them with a SonRtip lead. The implanted atrial lead in the latter person experienced a sudden increase in pacing threshold (4V/0.35ms).CONCLUSIONS: While short-term safety and stable technical performance of the SonRtip atrial lead could be confirmed, our study found an unexpectedly high malfunction rate over a longer follow-up period.
KW - Aged
KW - Aged, 80 and over
KW - Atrial Fibrillation/physiopathology
KW - Cardiac Resynchronization Therapy
KW - Cardiac Resynchronization Therapy Devices
KW - Equipment Failure
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Myocardial Contraction
UR - http://www.scopus.com/inward/record.url?scp=85071918609&partnerID=8YFLogxK
U2 - 10.1371/journal.pone.0222269
DO - 10.1371/journal.pone.0222269
M3 - Journal article
C2 - 31498840
SN - 1932-6203
VL - 14
SP - e0222269
JO - PLoS ONE
JF - PLoS ONE
IS - 9
M1 - e0222269
ER -