Daily vitamin D supplementation of infants up to the second experienced summer is recommended to prevent rickets and administration of vitamin K to neonates is recommended to prevent bleeding because of vitamin K deficiency. For some time, combination products of these two fat-soluble vitamins D3 and K2 have been available on the market in Austria, which are advertised as having health-promoting effects, such as improved bone mineralization and protection against vascular calcium deposits. The effect of a combined supplementation of vitamin D and vitamin K2 in children would be potentially beneficial from a physiological point of view in order to evaluate the effect, risks or undesirable side effects; however, beforehand dose finding and safety studies are required for the combined administration. In pediatrics, in particular, randomized controlled studies in children at risk and premature babies are necessary. As long as these data are not available, the administration of vitamin D in combination with vitamin K2 in childhood does not appear to be justified and therefore cannot be recommended.
|Translated title of the contribution
|Combined vitamin D and vitamin K supplements for children and adolescents: benefit or risk?: Recommendations of the nutrition committee of the Austrian Society for Pediatric and Adolescent Medicine (ÖGKJ)
|Number of pages
|Monatsschrift fur Kinderheilkunde
|Published - Jul 2021
ASJC Scopus subject areas
- Pediatrics, Perinatology and Child Health