OBJECTIVES: This study sought to investigate the outcome of high-risk and inoperable patients with severe symptomatic aortic stenosis undergoing transfemoral transcatheter aortic valve replacement (TAVR) in hospitals with (iOSCS) versus without institutional on-site cardiac surgery (no-iOSCS).
BACKGROUND: Current guidelines recommend the use of TAVR only in institutions with a department for cardiac surgery on site.
METHODS: In this analysis of the prospective multicenter Austrian TAVI registry, 1,822 consecutive high-risk patients with severe symptomatic aortic stenosis undergoing transfemoral TAVR were evaluated. A total of 290 (15.9%) underwent TAVR at no-iOSCS centers (no-iOSCS group), whereas the remaining 1,532 patients (84.1%) were treated in iOSCS centers (iOSCS group).
RESULTS: Patients of the no-iOSCS group had a higher perioperative risk defined by the logistic EuroSCORE (20.9% vs. 14.2%; p < 0.001) compared with patients treated in hospitals with iOSCS. Procedural survival was 96.9% in no-iOSCS centers and 98.6% in iOSCS centers (p = 0.034), whereas 30-day survival was 93.1% versus 96.0% (p = 0.039) and 1-year survival was 80.9% versus 86.1% (p = 0.017), respectively. After propensity score matching for confounders procedural survival was 96.9% versus 98.6% (p = 0.162), 93.1% versus 93.8% (p = 0.719) at 30 days, and 80.9% versus 83.4% (p = 0.402) at 1 year.
CONCLUSIONS: Patients undergoing transfemoral TAVR in hospitals without iOSCS had a significantly higher baseline risk profile. After propensity score matching short- and long-term mortality was similar between centers with and without iOSCS.
|Number of pages||8|
|Journal||JACC: Cardiovascular Interventions|
|Publication status||Published - 12 Nov 2018|
- Aged, 80 and over
- Aortic Valve Stenosis/diagnostic imaging
- Cardiac Surgical Procedures
- Cardiology Service, Hospital
- Catheterization, Peripheral/adverse effects
- Femoral Artery
- Prospective Studies
- Risk Assessment
- Risk Factors
- Severity of Illness Index
- Time Factors
- Transcatheter Aortic Valve Replacement/adverse effects
- Treatment Outcome
- on-site cardiac surgery
- aortic stenosis
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine