Immunotherapy of Equine Sarcoids-From: Early Approaches to Innovative Vaccines

Christoph Jindra, Edmund K Hainisch, Sabine Brandt

Research output: Journal article (peer-reviewed)Review article

2 Citations (Scopus)

Abstract

Horses and other equid species are frequently affected by bovine papillomavirus type 1 and/or 2 (BPV1, BPV2)-induced skin tumors termed sarcoids. Although sarcoids do not metastasize, they constitute a serious health problem due to their BPV1/2-mediated resistance to treatment and propensity to recrudesce in a more severe, multiple form following accidental or iatrogenic trauma. This review provides an overview on BPV1/2 infection and associated immune escape in the equid host and presents early and recent immunotherapeutic approaches in sarcoid management.

Original languageEnglish
Article number769
JournalVaccines
Volume11
Issue number4
DOIs
Publication statusPublished - Apr 2023

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