DDX3X facilitates adaption to proteotoxic stress by regulating the translation of MAPKAPK2 and the stability of TMCO1 via stress granules in multiple myeloma

Fengjuan Fan; Shijun Jiang; Enqi Ni; Zhengyufan Wang; Yajun Wang; Liping Zuo; Chi Ma; Sonia Vallet; Aoshuang Xu; Jian Xu; Klaus Podar; Chunyan Sun; Yu Hu

doi:10.1182/blood-2025-3944

DDX3X facilitates adaption to proteotoxic stress by regulating the translation of MAPKAPK2 and the stability of TMCO1 via stress granules in multiple myeloma

Fengjuan Fan
, Shijun Jiang
, Enqi Ni
, Zhengyufan Wang
, Yajun Wang
, Liping Zuo
, Chi Ma
, Sonia Vallet
, Aoshuang Xu
, Jian Xu
, Klaus Podar
, Chunyan Sun
, Yu Hu

Research output: Journal article (peer-reviewed) › Conference contribution to journal

Original language	English
Pages (from-to)	3944-3944
Journal	Blood
Volume	146
Issue number	Supplement 1
DOIs	https://doi.org/10.1182/blood-2025-3944
Publication status	Published - 03 Nov 2025

Access to Document

10.1182/blood-2025-3944

https://ashpublications.org/blood/article/146/Supplement%201/3944/550226/DDX3X-facilitates-adaption-to-proteotoxic-stress

Cite this

@article{acbd557947e1486aa71d447c58383714,

title = "DDX3X facilitates adaption to proteotoxic stress by regulating the translation of MAPKAPK2 and the stability of TMCO1 via stress granules in multiple myeloma",

author = "Fengjuan Fan and Shijun Jiang and Enqi Ni and Zhengyufan Wang and Yajun Wang and Liping Zuo and Chi Ma and Sonia Vallet and Aoshuang Xu and Jian Xu and Klaus Podar and Chunyan Sun and Yu Hu",

year = "2025",

month = nov,

day = "3",

doi = "10.1182/blood-2025-3944",

language = "English",

volume = "146",

pages = "3944--3944",

journal = "Blood",

issn = "0006-4971",

publisher = "Elsevier B.V.",

number = "Supplement 1",

}

TY - JOUR

T1 - DDX3X facilitates adaption to proteotoxic stress by regulating the translation of MAPKAPK2 and the stability of TMCO1 via stress granules in multiple myeloma

AU - Fan, Fengjuan

AU - Jiang, Shijun

AU - Ni, Enqi

AU - Wang, Zhengyufan

AU - Wang, Yajun

AU - Zuo, Liping

AU - Ma, Chi

AU - Vallet, Sonia

AU - Xu, Aoshuang

AU - Xu, Jian

AU - Podar, Klaus

AU - Sun, Chunyan

AU - Hu, Yu

PY - 2025/11/3

Y1 - 2025/11/3

U2 - 10.1182/blood-2025-3944

DO - 10.1182/blood-2025-3944

M3 - Conference contribution to journal

SN - 0006-4971

VL - 146

SP - 3944

EP - 3944

JO - Blood

JF - Blood

IS - Supplement 1

ER -