Computational Fluid Dynamic Simulations of Cerebral Aneurysms

Camillo Sherif, Gerhard Sommer, Peter Schiretz, Gerhard A Holzapfel

Research output: Contribution to book/report/conference proceedingChapter in book/report

Abstract

Computational fluid dynamics (CFD) simulations have been introduced to enable individualized risk prognosis for patients with unruptured cerebral aneurysms. The present contribution provides an overview of the biomechanical and physiological principles of aneurysm formation and rupture. It describes the computational steps of the CFD and the evaluated parameters. The clinical value of CFD is then discussed based on a recent literature review. Finally, we discuss current methodological limitations and possible future developments to overcome the actual drawbacks of CFD.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
Pages397-415
Number of pages19
Volume1462
DOIs
Publication statusPublished - Nov 2024

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1462
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Keywords

  • Intracranial Aneurysm/physiopathology
  • Humans
  • Hydrodynamics
  • Computer Simulation
  • Models, Cardiovascular
  • Aneurysm, Ruptured/physiopathology
  • Biomechanical Phenomena
  • Cerebrovascular Circulation/physiology
  • Cerebral aneurysm
  • Computational fluid dynamics
  • Simulation
  • Unruptured
  • Incidental

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology

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