A review of particle therapy for skull base tumors: Modern considerations and future directions

Eugen B. Hug; MacIej Pelak; Steven J. Frank; Piero Fossati

doi:10.14338/IJPT-20-00083

A review of particle therapy for skull base tumors: Modern considerations and future directions

Eugen B. Hug^*, MacIej Pelak, Steven J. Frank, Piero Fossati

^*Corresponding author for this work

Research output: Journal article (peer-reviewed) › Journal article

10 Citations (Scopus)

Abstract

Skull base tumors constitute one of the established indications for particle therapy, specifically proton therapy. However, a number of prognostic factors, practical clinical management issues, and the emerging role of carbon ion therapy remain subjects of active clinical investigation. This review summarizes these topics, assesses the present status, and reflects on future research directions focusing on the management of chordomas, one of the most aggressive skull base tumors. In addition, the role of particle therapy for benign tumors of the skull base, including pituitary adenoma and acoustic neuroma, is reviewed.

Original language	English
Pages (from-to)	168-178
Number of pages	11
Journal	International Journal of Particle Therapy
Volume	8
Issue number	1
DOIs	https://doi.org/10.14338/IJPT-20-00083
Publication status	Published - 01 Jun 2021
Externally published	Yes

Keywords

Carbon ion therapy
Chordoma
Particle therapy
Proton beam therapy
Skull base tumors

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Radiology, Nuclear Medicine and Imaging

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10.14338/IJPT-20-00083

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title = "A review of particle therapy for skull base tumors: Modern considerations and future directions",

abstract = "Skull base tumors constitute one of the established indications for particle therapy, specifically proton therapy. However, a number of prognostic factors, practical clinical management issues, and the emerging role of carbon ion therapy remain subjects of active clinical investigation. This review summarizes these topics, assesses the present status, and reflects on future research directions focusing on the management of chordomas, one of the most aggressive skull base tumors. In addition, the role of particle therapy for benign tumors of the skull base, including pituitary adenoma and acoustic neuroma, is reviewed.",

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author = "Hug, {Eugen B.} and MacIej Pelak and Frank, {Steven J.} and Piero Fossati",

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T2 - Modern considerations and future directions

AU - Hug, Eugen B.

AU - Pelak, MacIej

AU - Frank, Steven J.

AU - Fossati, Piero

PY - 2021/6/1

Y1 - 2021/6/1

N2 - Skull base tumors constitute one of the established indications for particle therapy, specifically proton therapy. However, a number of prognostic factors, practical clinical management issues, and the emerging role of carbon ion therapy remain subjects of active clinical investigation. This review summarizes these topics, assesses the present status, and reflects on future research directions focusing on the management of chordomas, one of the most aggressive skull base tumors. In addition, the role of particle therapy for benign tumors of the skull base, including pituitary adenoma and acoustic neuroma, is reviewed.

AB - Skull base tumors constitute one of the established indications for particle therapy, specifically proton therapy. However, a number of prognostic factors, practical clinical management issues, and the emerging role of carbon ion therapy remain subjects of active clinical investigation. This review summarizes these topics, assesses the present status, and reflects on future research directions focusing on the management of chordomas, one of the most aggressive skull base tumors. In addition, the role of particle therapy for benign tumors of the skull base, including pituitary adenoma and acoustic neuroma, is reviewed.

KW - Carbon ion therapy

KW - Chordoma

KW - Particle therapy

KW - Proton beam therapy

KW - Skull base tumors

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SN - 2331-5180

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JO - International Journal of Particle Therapy

JF - International Journal of Particle Therapy

IS - 1

ER -

A review of particle therapy for skull base tumors: Modern considerations and future directions

Abstract

Keywords

ASJC Scopus subject areas

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