Towards offline PET monitoring of proton therapy at MedAustron

Heide Meißner, Hermann Fuchs, Albert Hirtl, Christian Reschl, Markus Stock

Publikation: Beitrag in Fachzeitschrift (peer-reviewed)Artikel in Fachzeitschrift

11 Zitate (Scopus)

Abstract

The characteristic depth-dose profile of protons traveling through material is the main advantage of proton therapy over conventional radiotherapy with photons or electrons. However, uncertainties regarding the range of the protons in human tissue prevent to exploit the full potential of proton therapy. Therefore, a non-invasive in-vivo dose monitoring is desired. At the ion beam center MedAustron in Wiener Neustadt/Austria, patient treatment with proton beams started in December 2016. A PET/CT is available in close vicinity of the treatment rooms, exclusively dedicated to offline PET monitoring directly after the therapeutic irradiation. Preparations for a patient study include workflow tests under realistic clinical conditions using two different phantoms, irradiated with protons prior to the scan in the PET/CT. GATE simulations of the C-11 production are used as basis for the prediction of the PET measurement. We present results from the workflow tests in comparison with simulation results, and by this, we demonstrate the applicability of the PET monitoring at the MedAustron facility.

OriginalspracheEnglisch
Seiten (von - bis)59-65
Seitenumfang7
FachzeitschriftZeitschrift fur Medizinische Physik
Jahrgang29
Ausgabenummer1
DOIs
PublikationsstatusVeröffentlicht - Feb. 2019
Extern publiziertJa

Fingerprint

Untersuchen Sie die Forschungsthemen von „Towards offline PET monitoring of proton therapy at MedAustron“. Zusammen bilden sie einen einzigartigen Fingerprint.

Dieses zitieren