TY - JOUR
T1 - Gender-based comorbidity in benign paroxysmal positional vertigo
AU - Ogun, Oluwaseye Ayoola
AU - Janky, Kristen L
AU - Cohn, Edward S
AU - Büki, Bela
AU - Lundberg, Yunxia Wang
N1 - Publisher Copyright:
© 2014 Ogun et al.
PY - 2014/9/4
Y1 - 2014/9/4
N2 - It has been noted that benign paroxysmal positional vertigo (BPPV) may be associated with certain disorders and medical procedures. However, most studies to date were done in Europe, and epidemiological data on the United States (US) population are scarce. Gender-based information is even rarer. Furthermore, it is difficult to assess the relative prevalence of each type of association based solely on literature data, because different comorbidities were reported by various groups from different countries using different patient populations and possibly different inclusion/exclusion criteria. In this study, we surveyed and analyzed a large adult BPPV population (n = 1,360 surveyed, 227 completed, most of which were recurrent BPPV cases) from Omaha, NE, US, and its vicinity, all diagnosed at Boys Town National Research Hospital (BTNRH) over the past decade using established and consistent diagnostic criteria. In addition, we performed a retrospective analysis of patients' diagnostic records (n = 1,377, with 1,360 adults and 17 children). The following comorbidities were found to be significantly more prevalent in the BPPV population when compared to the age- and gender-matched general population: ear/hearing problems, head injury, thyroid problems, allergies, high cholesterol, headaches, and numbness/paralysis. There were gender differences in the comorbidities. In addition, familial predisposition was fairly common among the participants. Thus, the data confirm some previously reported comorbidities, identify new ones (hearing loss, thyroid problems, high cholesterol, and numbness/paralysis), and suggest possible predisposing and triggering factors and events for BPPV.
AB - It has been noted that benign paroxysmal positional vertigo (BPPV) may be associated with certain disorders and medical procedures. However, most studies to date were done in Europe, and epidemiological data on the United States (US) population are scarce. Gender-based information is even rarer. Furthermore, it is difficult to assess the relative prevalence of each type of association based solely on literature data, because different comorbidities were reported by various groups from different countries using different patient populations and possibly different inclusion/exclusion criteria. In this study, we surveyed and analyzed a large adult BPPV population (n = 1,360 surveyed, 227 completed, most of which were recurrent BPPV cases) from Omaha, NE, US, and its vicinity, all diagnosed at Boys Town National Research Hospital (BTNRH) over the past decade using established and consistent diagnostic criteria. In addition, we performed a retrospective analysis of patients' diagnostic records (n = 1,377, with 1,360 adults and 17 children). The following comorbidities were found to be significantly more prevalent in the BPPV population when compared to the age- and gender-matched general population: ear/hearing problems, head injury, thyroid problems, allergies, high cholesterol, headaches, and numbness/paralysis. There were gender differences in the comorbidities. In addition, familial predisposition was fairly common among the participants. Thus, the data confirm some previously reported comorbidities, identify new ones (hearing loss, thyroid problems, high cholesterol, and numbness/paralysis), and suggest possible predisposing and triggering factors and events for BPPV.
KW - Adolescent
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Benign Paroxysmal Positional Vertigo/epidemiology
KW - Comorbidity
KW - Female
KW - Genetic Predisposition to Disease
KW - Headache/epidemiology
KW - Hearing Loss/epidemiology
KW - Humans
KW - Male
KW - Middle Aged
KW - Nebraska/epidemiology
KW - Recurrence
KW - Retrospective Studies
KW - Sex Factors
KW - Young Adult
UR - http://www.scopus.com/inward/record.url?scp=84907053697&partnerID=8YFLogxK
U2 - 10.1371/journal.pone.0105546
DO - 10.1371/journal.pone.0105546
M3 - Journal article
C2 - 25187992
SN - 1932-6203
VL - 9
SP - e105546
JO - PLoS ONE
JF - PLoS ONE
IS - 9
M1 - e105546
ER -