TY - JOUR
T1 - Fluorescence-guided resection of extracranial soft tissue tumour infiltration in atypical meningioma
AU - Scheichel, Florian
AU - Ungersboeck, Karl
AU - Kitzwoegerer, Melitta
AU - Marhold, Franz
N1 - Publisher Copyright:
© 2017, Springer-Verlag Wien.
PY - 2017/6/1
Y1 - 2017/6/1
N2 - The exact role of 5-aminolevulinic acid (5-ALA) fluorescence-guided meningioma resection is as yet unclear. Although most of the meningiomas show positive fluorescence, the influence on outcome, fluorescence heterogeneity within the tumour, the correlation between fluorescence and the proliferation rate, as well as different quantitative measurements are a matter of debate. Positive fluorescence in bone infiltrative meningiomas is well described, whereas little data exist about 5-ALA fluorescence within soft tissue infiltration. We add a case of histologically confirmed fluorescent tumour infiltration into soft tissue. A 78-year-old woman underwent resection of an atypical meningioma at the University Hospital of St. Poelten. Preoperative imaging showed tumour infiltration throughout the calvaria. 5-ALA fluorescence of the tumour as well as bone, periost and temporal muscle helped to perform a gross total resection. Histological examination showed an atypical meningioma (WHO Grade II) and gave proof of tumour infiltration of the bone and temporal muscle. With the aid of 5-ALA fluorescence, a gross total resection could be performed.
AB - The exact role of 5-aminolevulinic acid (5-ALA) fluorescence-guided meningioma resection is as yet unclear. Although most of the meningiomas show positive fluorescence, the influence on outcome, fluorescence heterogeneity within the tumour, the correlation between fluorescence and the proliferation rate, as well as different quantitative measurements are a matter of debate. Positive fluorescence in bone infiltrative meningiomas is well described, whereas little data exist about 5-ALA fluorescence within soft tissue infiltration. We add a case of histologically confirmed fluorescent tumour infiltration into soft tissue. A 78-year-old woman underwent resection of an atypical meningioma at the University Hospital of St. Poelten. Preoperative imaging showed tumour infiltration throughout the calvaria. 5-ALA fluorescence of the tumour as well as bone, periost and temporal muscle helped to perform a gross total resection. Histological examination showed an atypical meningioma (WHO Grade II) and gave proof of tumour infiltration of the bone and temporal muscle. With the aid of 5-ALA fluorescence, a gross total resection could be performed.
KW - Aged
KW - Female
KW - Fluorescence
KW - Humans
KW - Meningeal Neoplasms/pathology
KW - Meningioma/pathology
KW - Neurosurgical Procedures/adverse effects
KW - Postoperative Complications
KW - Soft Tissue Neoplasms/secondary
KW - Surgery, Computer-Assisted/adverse effects
UR - http://www.scopus.com/inward/record.url?scp=85017240757&partnerID=8YFLogxK
U2 - 10.1007/s00701-017-3166-4
DO - 10.1007/s00701-017-3166-4
M3 - Journal article
C2 - 28397137
SN - 0001-6268
VL - 159
SP - 1027
EP - 1031
JO - Acta Neurochirurgica
JF - Acta Neurochirurgica
IS - 6
ER -