TY - JOUR
T1 - Dose-dependent changes in real-life affective well-being in healthy community-based individuals with mild to moderate childhood trauma exposure
AU - Berhe, Oksana
AU - Moessnang, Carolin
AU - Reichert, Markus
AU - Ma, Ren
AU - Höflich, Anna
AU - Tesarz, Jonas
AU - Heim, Christine M
AU - Ebner-Priemer, Ulrich
AU - Meyer-Lindenberg, Andreas
AU - Tost, Heike
N1 - Funding Information:
We thank Gabriela Gan, PhD, Beate Höchemer, MA, Janina I. Schweiger, MD, Carina Sebald, MSc, Alexander Moldavski, MD, Mirjam Melzer, MSc, and our research assistants for valuable support.
Publisher Copyright:
© 2023, The Author(s).
PY - 2023/4/20
Y1 - 2023/4/20
N2 - BACKGROUND: Childhood trauma exposures (CTEs) are frequent, well-established risk factor for the development of psychopathology. However, knowledge of the effects of CTEs in healthy individuals in a real life context, which is crucial for early detection and prevention of mental disorders, is incomplete. Here, we use ecological momentary assessment (EMA) to investigate CTE load-dependent changes in daily-life affective well-being and psychosocial risk profile in n = 351 healthy, clinically asymptomatic, adults from the community with mild to moderate CTE.FINDINGS: EMA revealed significant CTE dose-dependent decreases in real-life affective valence (p = 0.007), energetic arousal (p = 0.032) and calmness (p = 0.044). Psychosocial questionnaires revealed a broad CTE-related psychosocial risk profile with dose-dependent increases in mental health risk-associated features (e.g., trait anxiety, maladaptive coping, loneliness, daily hassles; p values < 0.003) and a corresponding decrease in factors protective for mental health (e.g., life satisfaction, adaptive coping, optimism, social support; p values < 0.021). These results were not influenced by age, sex, socioeconomic status or education.CONCLUSIONS: Healthy community-based adults with mild to moderate CTE exhibit dose-dependent changes in well-being manifesting in decreases in affective valence, calmness and energy in real life settings, as well as a range of established psychosocial risk features associated with mental health risk. This indicates an approach to early detection, early intervention, and prevention of CTE-associated psychiatric disorders in this at-risk population, using ecological momentary interventions (EMI) in real life, which enhance established protective factors for mental health, such as green space exposure, or social support.
AB - BACKGROUND: Childhood trauma exposures (CTEs) are frequent, well-established risk factor for the development of psychopathology. However, knowledge of the effects of CTEs in healthy individuals in a real life context, which is crucial for early detection and prevention of mental disorders, is incomplete. Here, we use ecological momentary assessment (EMA) to investigate CTE load-dependent changes in daily-life affective well-being and psychosocial risk profile in n = 351 healthy, clinically asymptomatic, adults from the community with mild to moderate CTE.FINDINGS: EMA revealed significant CTE dose-dependent decreases in real-life affective valence (p = 0.007), energetic arousal (p = 0.032) and calmness (p = 0.044). Psychosocial questionnaires revealed a broad CTE-related psychosocial risk profile with dose-dependent increases in mental health risk-associated features (e.g., trait anxiety, maladaptive coping, loneliness, daily hassles; p values < 0.003) and a corresponding decrease in factors protective for mental health (e.g., life satisfaction, adaptive coping, optimism, social support; p values < 0.021). These results were not influenced by age, sex, socioeconomic status or education.CONCLUSIONS: Healthy community-based adults with mild to moderate CTE exhibit dose-dependent changes in well-being manifesting in decreases in affective valence, calmness and energy in real life settings, as well as a range of established psychosocial risk features associated with mental health risk. This indicates an approach to early detection, early intervention, and prevention of CTE-associated psychiatric disorders in this at-risk population, using ecological momentary interventions (EMI) in real life, which enhance established protective factors for mental health, such as green space exposure, or social support.
KW - Childhood trauma exposure
KW - Community sample
KW - Ecological momentary assessment
KW - Mental health risk
UR - http://www.scopus.com/inward/record.url?scp=85153519348&partnerID=8YFLogxK
U2 - 10.1186/s40479-023-00220-5
DO - 10.1186/s40479-023-00220-5
M3 - Journal article
C2 - 37076921
SN - 2051-6673
VL - 10
SP - 14
JO - Borderline Personality Disorder and Emotion Dysregulation
JF - Borderline Personality Disorder and Emotion Dysregulation
IS - 1
M1 - 14
ER -